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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Elizabeth Moylan
Welcome to BMC Biology published by BioMed Central
BMC Biology - the flagship biology journal of the BMC series - publishes research and methodology articles of special importance and broad interest in any area of biology and biomedical sciences. BMC Biology (ISSN 1741-7007) is covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
BMC Biology 2008, 6 :41
Froghoppers jump by flexing a bow-like structure between their hind legs and wings made of hard cuticle and a rubbery protein called resilin, which stores the energy needed to propel the insect forwards in a catapult-like jump.
BMC Biology 2008, 6 :40
Germline transmission of a bicistronic vector using the 2A peptide to allow co-translational cleavage is stable in mice and shows no developmental side-effects, giving a superior alternative to the internal ribosomal entry site for expressing multiple transgenes.
BMC Biology 2008, 6 :39
Cholesterol depletion will not help combat prion diseases because although inhibitors of cholesterol synthesis reduce the formation of disease-associated prion protein isoforms (PrPSc), polyunsaturated fatty acids that reduce cholesterol levels actually significantly increase PrPSc formation.
BMC Biology 2008, 6 :38
Parasitic wasps suppress the immune systems of their caterpillar hosts by injecting a polydnavirus, exposing the viral cystation virulence factors to strong selection and maintaining this complex tri-component system through such virus-host co-evolution.
BMC Biology 2008, 6 :37
Erythropoietin (EPO), the blood-boosting hormone used for medical treatment and athletic doping, enhances hippocampus-dependent memory in mice by directly influencing neurons rather than as a side-effect of increased red blood cell production.
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Research article
The Caenorhabditis chemoreceptor gene families James H Thomas, Hugh M Robertson BMC Biology 2008, 6 :42 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Resilin and cuticle form a composite structure for energy storage in jumping by froghopper insects Malcolm Burrows, Stephen R Shaw, Gregory P Sutton BMC Biology 2008, 6 :41 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Use of the viral 2A peptide for bicistronic expression in transgenic mice Georgios Trichas, Jo Begbie, Shankar Srinivas BMC Biology 2008, 6 :40 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells Clive Bate, Mourad Tayebi, Luisa Diomede, Mario Salmona, Alun Williams BMC Biology 2008, 6 :39 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research article
Viral cystatin evolution and three-dimensional structure modelling: A case of directional selection acting on a viral protein involved in a host-parasitoid interaction C BMC Biology 2008, 6 :38 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Erythropoietin enhances hippocampal long-term potentiation and memory Bartosz Adamcio, Derya Sargin, Alicja Stradomska, Lucian Medrihan, Christoph Gertler, Fabian Theis, Mingyue Zhang, Michael M BMC Biology 2008, 6 :37 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [F1000 Biology ]
Research article
Complex chloroplast RNA metabolism: just debugging the genetic programme? Uwe G Maier, Andrew Bozarth, Helena T Funk, Stefan Zauner, Stefan A Rensing, Christian Schmitz-Linneweber, Thomas B BMC Biology 2008, 6 :36 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Evolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages Susan Bassham, Cristian Ca BMC Biology 2008, 6 :35 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals Vidushi S Patel, Steven JB Cooper, Janine E Deakin, Bob Fulton, Tina Graves, Wesley C Warren, Richard K Wilson, Jennifer AM Graves BMC Biology 2008, 6 :34 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Systematic comparison and reconstruction of sea urchin (Echinoidea) internal anatomy: a novel approach using magnetic resonance imaging Alexander Ziegler, Cornelius Faber, Susanne Mueller, Thomas Bartolomaeus BMC Biology 2008, 6 :33 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia Collins O Odhiambo, Walter Otieno, Christine Adhiambo, Michael M Odera, Jos BMC Medicine 2008, 6 :23 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson BMC Medicine 2008, 6 :14 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Collagen density promotes mammary tumor initiation and progression Paolo P Provenzano, David R Inman, Kevin W Eliceiri, Justin G Knittel, Long Yan, Curtis T Rueden, John G White, Patricia J Keely BMC Medicine 2008, 6 :11 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
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Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario Laurent Briollais, Yuanyuan Wang, Isaac Rajendram, Venus Onay, Ellen Shi, Julia Knight, Hilmi Ozcelik BMC Medicine 2007, 5 :22 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Corticortophin releasing factor 2 receptor agonist treatment significantly slows disease progression in mdx mice Richard T Hinkle, Frank R Lefever, Elizabeth T Dolan, Deborah L Reichart, Jefferey A Dietrich, Kathryn E Gropp, Robert I Thacker, Jeffrey P Demuth, Paula J Stevens, Xiaoyan A Qu, Alex R Varbanov, Feng Wang, Robert J Isfort BMC Medicine 2007, 5 :18 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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How to optimise the coverage rate of infant and adult immunisations in Europe Heinz-J Schmitt, Robert Booy, Robert Aston, Pierre Van Damme, R Fabian Schumacher, Magda Campins, Carlos Rodrigo, Terho Heikkinen, Catherine Weil-Olivier, Adam Finn, Per Olc BMC Medicine 2007, 5 :11 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact of Nina K Bartels, Jan B BMC Medicine 2007, 5 :1 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Collagen reorganization at the tumor-stromal interface facilitates local invasion Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White, Patricia J Keely BMC Medicine 2006, 4 :38 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Grey matter changes can improve the prediction of schizophrenia in subjects at high risk Dominic E Job, Heather C Whalley, Andrew M McIntosh, David GC Owens, Eve C Johnstone, Stephen M Lawrie BMC Medicine 2006, 4 :29 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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