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Advancements in Male Contraception

©  © Flickr: Zappy’s Technology Solutions. Attribution 4.0 International (CC BY 4.0)​​​​​​​Male hormonal contraception has been an active area of research for almost 50 years. However, at present, there is still a gap in contraceptive options for couples, and more particularly, effective reversible contraceptives for men. Male hormonal methods still need to be optimized, and efforts to do so are currently under way. 

While female contraceptives are very effective at preventing unintended pregnancy, they are not free from many undesirable and potentially dangerous side effects, and effective male contraceptive options are limited to condoms and withdrawal. A vasectomy provides a long-term solution but its uncertainty in reversibility is a major disincentive to contraceptive use for many men who wish to take active responsibility for family planning. This article collection further explores the most recent research documenting the advancements in male contraception.

Submission is open to everyone, and all submitted manuscripts will be peer-reviewed through the regular journal review process. Manuscripts should be formatted according to the relevant journal submission guidelines and submitted via the online submission system. In the submission system please ensure that the correct thematic series title is chosen from the additional information tab. Please also indicate clearly in the covering letter which thematic series you are submitting to.

If you have any research you would like us to consider for inclusion in our special collection, please submit directly to Basic and Clinical Andrology

Image: © Flickr: Zappy’s Technology Solutions. Attribution 4.0 International (CC BY 4.0)

 

  1. Since the release of the combined oral contraceptive pill in 1960, women have shouldered the burden of contraception and family planning. Over 60 years later, this is still the case as the only practical, effe...

    Authors: Eli J. Louwagie, Garrett F.L. Quinn, Kristi L. Pond and Keith A. Hansen
    Citation: Basic and Clinical Andrology 2023 33:30
  2. Even after decades of research men still lack reliable and reversible contraceptive methods comparable to female methods of contraception. Traditional methods of male contraception present a high failure rate ...

    Authors: Barkha Khilwani, Ayesha Badar, Abdul S. Ansari and Nirmal K. Lohiya
    Citation: Basic and Clinical Andrology 2020 30:2
  3. Chemical sterilization with zinc gluconate is being developed due to its permanent contraceptive effect in prepubertal dogs. In this study, five healthy adult dogs were selected randomly. Semen samples were co...

    Authors: Dorna Rafatmah, Asghar Mogheiseh and Davoud Eshghi
    Citation: Basic and Clinical Andrology 2019 29:12
  4. Today, a vast arsenal of contraceptive methods interfering at different levels of the female reproductive axis is available. This is not the case for men for whom, until now, there is no reliable male reversib...

    Authors: Joël R. Drevet
    Citation: Basic and Clinical Andrology 2018 28:12
  5. Development of a non-hormonal long-acting reversible contraceptive for men could have a significant impact on reducing unintended pregnancies. Vasalgelâ„¢ is a high molecular weight polymer consisting of styrene...

    Authors: Donald Waller, David Bolick, Elaine Lissner, Christopher Premanandan and Gary Gamerman
    Citation: Basic and Clinical Andrology 2017 27:8
  6. Options for male contraception are limited. The purpose of this study was to use a nonhuman primate model to evaluate Vasalgelâ„¢, a high molecular weight polymer being developed as a contraceptive device for men.

    Authors: Angela Colagross-Schouten, Marie-Josee Lemoy, Rebekah I. Keesler, Elaine Lissner and Catherine A. VandeVoort
    Citation: Basic and Clinical Andrology 2017 27:4
  7. Since the 1970s, international research on male contraception has been actively pursued. Hormonal and non-hormonal methods (thermal, chemical) have been tested, leading to clinical trials of interest to thousa...

    Authors: Jean-Claude Soufir
    Citation: Basic and Clinical Andrology 2017 27:3
  8. Vasectomy is currently the only long-acting contraceptive option available for men, despite increasing demand and potentially significant positive impacts on human health of additional male contraceptive optio...

    Authors: Donald Waller, David Bolick, Elaine Lissner, Christopher Premanandan and Gary Gamerman
    Citation: Basic and Clinical Andrology 2016 26:6