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BMC Research highlights

Image: Interacting network of CREB targets, BMC Cancer
BMC Cancer 2008, 8:264
Genes involved in DNA repair, signalling, oncogenesis and autophagy are regulated by cAMP Response Element Binding Protein (CREB) in myeloid leukemia cells, providing insights into pathogenesis and potential targets for therapy

Image credit: Jim Gathany, CDC (public domain)
BMC Genomics 2008, 9:425
Comparative genomics of small RNA regulatory components - miRNA, siRNA and piRNA - in the three important mosquito vectors reveals novel motifs indicating that a variety of transcription control mechanisms operate in mosquito anti-viral defense pathways.

BMC Genomics 2008, 9:408
A combination of microarrays, RNA interference and comparative genomics uncovered direct regulatory targets of Sox10, a transcription factor implicated in the development of several important cell lineages, including the peripheral glia.

BMC Biology 2008, 6:38
Parasitic wasps suppress the immune systems of their caterpillar hosts by injecting a polydnavirus, exposing the viral cystation virulence factors to strong selection and maintaining this complex tri-component system through such virus-host co-evolution.

Genome Biology 2008, 9:R134
Transcriptional analysis of chromatin regulator mutants in Drosophila melanogaster identified clusters of functionally related genes conserved in other insect species.


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BMC Author profile

Liqun Lu
National University of Singapore


BMC Latest research articles

Research article
TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells
Ville Hietakangas, Stephen M Cohen
BMC Cancer 2008, 8:282 (3October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases
Nicholas N Lyssenko, Yana Miteva, Simon Gilroy, Wendy Hanna-Rose, Robert A Schlegel
BMC Developmental Biology 2008, 8:96 (2October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Genome-wide identification, organization and phylogenetic analysis of Dicer-like, Argonaute and RNA-dependent RNA Polymerase gene families and their expression analysis during reproductive development and stress in rice
Meenu Kapoor, Rita Arora, Tenisha Lama, Aashima Nijhawan, Jitendra P Khurana, Akhilesh K Tyagi, Sanjay Kapoor
BMC Genomics 2008, 9:451 (1October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland
Holly E Barker, Gordon K Smyth, James Wettenhall, Teresa A Ward, Mary L Bath, Geoffrey J Lindeman, Jane E Visvader
BMC Developmental Biology 2008, 8:94 (1October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy
Patricia C Sanchez-Diaz, Tarea L Burton, Suzanne C Burns, Jaclyn Y Hung, Luiz O. F. Penalva
BMC Cancer 2008, 8:280 (30September2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells
Ana Slipicevic, Kjersti Jorgensen, Martina Skrede, Anne Katrine Ree Rosnes, Gunhild Troen, Ben Davidson, Vivi Ann Florenes
BMC Cancer 2008, 8:276 (30September2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]






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