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Case Western Reserve University, an independent research university, offers world-class academic programs in Cleveland's culturally vibrant University Circle. The university counts 15 Nobel laureates among its alumni and current and former faculty.
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Work published with BioMed Central in the last 12 months by researchers at Case Western Reserve University
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Research
Could FIV zoonosis responsible of the breakdown of the pathocenosis which has reduced the European CCR5-Delta32 allele frequencies? Faure E Virology Journal 2008, 5 :119 (16 October 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Protective effect of KCNH2 single nucleotide polymorphism K897T in LQTS families and identification of novel KCNQ1 and KCNH2 mutations Zhang X, Chen S, Zhang L, Liu M, Redfearn S, Bryant RM, Oberti C, Vincent GM, Wang QK BMC Medical Genetics 2008, 9 :87 (23 September 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Generation of diverse neuronal subtypes in cloned populations of stem-like cells Varga BV, Hádinger N, Gócza E, Dulberg V, Demeter K, Madarász E, Herberth B BMC Developmental Biology 2008, 8 :89 (22 September 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Case Report
Late development of esophageal stricture following radiation and chemotherapy for small cell carcinoma of the lung: A case report Zhang MA, Trillis CM Cases Journal 2008, 1 :169 (19 September 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
MeDor: a metaserver for predicting protein disorder Lieutaud P, Canard B, Longhi S BMC Genomics 2008, 9 (Suppl 2):S25 (16 September 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Interference Screw vs. Suture Anchor Fixation for Open Subpectoral Biceps Tenodesis: Does it Matter? Millett PJ, Sanders B, Gobezie R, Braun S, Warner JJP BMC Musculoskeletal Disorders 2008, 9 :121 (15 September 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study Kratzer W, Haenle MM, Voegtle A, Mason RA, Akinli AS, Hirschbuehl K, Schuler A, Kaechele V, the Roemerstein study group BMC Gastroenterology 2008, 8 :41 (15 September 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Poster presentation
Associations between continuous measures of disease activity in adult RA and the pediatric ACR response measures: a secondary analysis of JIA data Ringold S, Chon Y, Singer NG Pediatric Rheumatology 2008, 6 (Suppl 1):P121 (15 September 2008) [Abstract ] [Full text ] [PDF ]
Short report
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G Molecular Neurodegeneration 2008, 3 :13 (11 September 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Case report
Fatal hemolytic anemia associated with metformin: A case report Packer CD, Hornick TR, Augustine SA Journal of Medical Case Reports 2008, 2 :300 (10 September 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements Esnault C, Priet S, Ribet D, Heidmann O, Heidmann T Retrovirology 2008, 5 :75 (14 August 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
The Collaborative Lithium Trials (CoLT): specific aims, methods, and implementation Findling RL, Frazier JA, Kafantaris V, Kowatch R, McClellan J, Pavuluri M, Sikich L, Hlastala S, Hooper SR, Demeter CA, Bedoya D, Brownstein B, Taylor-Zapata P Child and Adolescent Psychiatry and Mental Health 2008, 2 :21 (12 August 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Study protocol
The One-stop trial: Does electronic referral and booking by the general practitioner (GPs) to outpatient day case surgery reduce waiting time and costs? A randomized controlled trial protocol Augestad KM, Revhaug A, Vonen B, Johnsen R, Lindsetmo RO BMC Surgery 2008, 8 :14 (11 August 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Retraction
Retraction: Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors Weiner SJ, Neragi-Miandoab S Journal of Carcinogenesis 2008, 7 :4 (8 August 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
The plant Apolipoprotein D ortholog protects Arabidopsis against oxidative stress Charron JBF, Ouellet F, Houde M, Sarhan F BMC Plant Biology 2008, 8 :86 (31 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in peri-urban Kampala, UgandaAsiimwe BB, Ghebremichael S, Kallenius G, Koivula T, Joloba ML BMC Infectious Diseases 2008, 8 :101 (28 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Review
Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors Weiner SJ, Neragi-Miandoab S Journal of Carcinogenesis 2008, 7 :3 (28 July 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Dominant negative mutant Cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat Jadlowsky JK, Nojima M, Schulte A, Geyer M, Okamoto T, Fujinaga K Retrovirology 2008, 5 :63 (11 July 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Antimalarial drug use in general populations of tropical Africa Gardella F, Assi S, Simon F, Bogreau H, Eggelte T, Ba F, Foumane V, Henry MC, Kientega PT, Basco L, Trape JF, Lalou R, Martelloni M, Desbordes M, Baragatti M, Briolant S, Almeras L, Pradines B, Fusai T, Rogier C Malaria Journal 2008, 7 :124 (8 July 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia Parimi N, Tromp G, Kuivaniemi H, Nien JK, Gomez R, Romero R, Goddard KAB BMC Medical Genetics 2008, 9 :60 (3 July 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Risk assessment does not explain high prevalence of gestational diabetes mellitus in a large group of Sardinian women Murgia C, Berria R, Minerba L, Sulis S, Murenu M, Portoghese E, Garau N, Zedda P, Melis GB Reproductive Biology and Endocrinology 2008, 6 :26 (2 July 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Methodology
Autoimmunity in gestational diabetes mellitus in Sardinia: a preliminary case-control report Murgia C, Orrù M, Portoghese E, Garau N, Zedda P, Berria R, Motzo C, Sulis S, Murenu M, Paoletti AM, Melis GB Reproductive Biology and Endocrinology 2008, 6 :24 (29 June 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Study protocol
Should the surgeon or the general practitioner (GP) follow up patients after surgery for colon cancer? A randomized controlled trial protocol focusing on quality of life, cost-effectiveness and serious clinical events Augestad KM, Vonen B, Aspevik R, Nestvold T, Ringberg U, Johnsen R, Norum J, Lindsetmo RO BMC Health Services Research 2008, 8 :137 (25 June 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes i n vitro Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM Journal of Inflammation 2008, 5 :9 (13 June 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Review
Uracil within DNA: an actor of antiviral immunity Sire J, Quérat G, Esnault C, Priet S Retrovirology 2008, 5 :45 (5 June 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Tailoring an intervention to the context and system redesign related to the intervention: A case study of implementing shared medical appointments for diabetes Kirsh SR, Lawrence RH, Aron DC Implementation Science 2008, 3 :34 (4 June 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Association of ABCB1 genetic variants with renal function in Africans and in Caucasians Bochud M, Eap CB, Maillard M, Johnson T, Vollenweider P, Bovet P, Elston RC, Bergmann S, Beckmann JS, Waterworth DM, Mooser V, Gabriel A, Burnier M BMC Medical Genomics 2008, 1 :21 (2 June 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Short report
Association of intervention outcomes with practice capacity for change: Subgroup analysis from a group randomized trial Litaker D, Ruhe M, Weyer S, Stange KC Implementation Science 2008, 3 :25 (16 May 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
The genome sequence of the model ascomycete fungus Podospora anserina Espagne E, Lespinet O, Malagnac F, Da Silva C, Jaillon O, Porcel BM, Couloux A, Aury JM, Ségurens B, Poulain J, Anthouard V, Grossetete S, Khalili H, Coppin E, Déquard-Chablat M, Picard M, Contamine V, Arnaise S, Bourdais A, Berteaux-Lecellier V, Gautheret D, de Vries RP, Battaglia E, Coutinho PM, Danchin EGJ, Henrissat B, Khoury REL, Sainsard-Chanet A, Boivin A, Pinan-Lucarré B, Sellem CH, Debuchy R, Wincker P, Weissenbach J, Silar P Genome Biology 2008, 9 :R77 (6 May 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The abdomen of Drosophila : does planar cell polarity orient the neurons of mechanosensory bristles? Fabre CCG, Casal J, Lawrence PA Neural Development 2008, 3 :12 (30 April 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Collagen density promotes mammary tumor initiation and progression Provenzano PP, Inman DR, Eliceiri KW, Knittel JG, Yan L, Rueden CT, White JG, Keely PJ BMC Medicine 2008, 6 :11 (28 April 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists Mosley JD, Keri RA BMC Medical Genomics 2008, 1 :11 (25 April 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Enhanced detection of gametocytes by magnetic deposition microscopy predicts higher potential for Plasmodium falciparum transmission Karl S, David M, Moore L, Grimberg BT, Michon P, Mueller I, Zborowski M, Zimmerman PA Malaria Journal 2008, 7 :66 (25 April 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Case report
Elevated maternal lipoprotein (a) and neonatal renal vein thrombosis: a case report Subbiah V, Parimi P Journal of Medical Case Reports 2008, 2 :106 (10 April 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of a novel KCNQ1 mutation associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long QT syndrome in a Chinese family Zhang S, Yin K, Ren X, Wang P, Zhang S, Cheng L, Yang J, Liu JY, Liu M, Wang QK BMC Medical Genetics 2008, 9 :24 (9 April 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Characterization of the Shewanella oneidensis Fur gene: roles in iron and acid tolerance response Yang Y, Harris DP, Luo F, Wu L, Parsons AB, Palumbo AV, Zhou J BMC Genomics 2008, 9 (Suppl 1):S11 (20 March 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Gene flow rise with habitat fragmentation in the bog fritillary butterfly (Lepidoptera: Nymphalidae) Nève G, Barascud B, Descimon H, Baguette M BMC Evolutionary Biology 2008, 8 :84 (17 March 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Poster presentation
Novel models for the prediction of mortality after traumatic brain injury requiring intensive care Hyam JA, Welch CA, Harrison DA, Menon DK Critical Care 2008, 12 (Suppl 2):P107 (13 March 2008) [Full text ] [PDF ]
Research article
Analyzing stochastic transcription to elucidate the nucleoid's organization Riva A, Carpentier AS, Barloy-Hubler F, Chéron A, Hénaut A BMC Genomics 2008, 9 :125 (10 March 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Discovering gene annotations in biomedical text databases Cakmak A, Ozsoyoglu G BMC Bioinformatics 2008, 9 :143 (6 March 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
AtMRP6 /AtABCC6 , an ATP-Binding Cassette transporter gene expressed during early steps of seedling development and up-regulated by cadmium in Arabidopsis thaliana Gaillard S, Jacquet H, Vavasseur A, Leonhardt N, Forestier C BMC Plant Biology 2008, 8 :22 (28 February 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A gene pattern mining algorithm using interchangeable gene sets for prokaryotes Hu M, Choi K, Su W, Kim S, Yang J BMC Bioinformatics 2008, 9 :124 (26 February 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Characterization and partial purification of Candida albicans Secretory IL-12 Inhibitory Factor Wang M, Mukherjee PK, Chandra J, Lattif AA, McCormick TS, Ghannoum MA BMC Microbiology 2008, 8 :31 (19 February 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Microarray data mining using landmark gene-guided clustering Chopra P, Kang J, Yang J, Cho HJ, Kim HS, Lee MG BMC Bioinformatics 2008, 9 :92 (11 February 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Equilibrium model selection: dTTP induced R1 dimerization Radivoyevitch T BMC Systems Biology 2008, 2 :15 (4 February 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Workforce analysis using data mining and linear regression to understand HIV/AIDS prevalence patterns Madigan EA, Curet OL, Zrinyi M Human Resources for Health 2008, 6 :2 (31 January 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Clinical Ethics Consultation: Examining how American and Japanese experts analyze an Alzheimer's case Nagao N, Aulisio MP, Nukaga Y, Fujita M, Kosugi S, Youngner S, Akabayashi A BMC Medical Ethics 2008, 9 :2 (29 January 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Response to M. tuberculosis selected RD1 peptides in Ugandan HIV-infected patients with smear positive pulmonary tuberculosis: a pilot study Goletti D, Carrara S, Mayanja-Kizza H, Baseke J, Mugerwa MA, Girardi E, Toossi Z BMC Infectious Diseases 2008, 8 :11 (28 January 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Software
Generating samples for association studies based on HapMap data Li J, Chen Y BMC Bioinformatics 2008, 9 :44 (24 January 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling Robbins SH, Walzer T, Dembélé D, Thibault C, Defays A, Bessou G, Xu H, Vivier E, Sellars ML, Pierre P, Sharp FR, Chan S, Kastner P, Dalod M Genome Biology 2008, 9 :R17 (24 January 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Marine mimivirus relatives are probably large algal viruses Monier A, Larsen JB, Sandaa RA, Bratbak G, Claverie JM, Ogata H Virology Journal 2008, 5 :12 (23 January 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Slow GABAA mediated synaptic transmission in rat visual cortex Sceniak MP, MacIver MB BMC Neuroscience 2008, 9 :8 (16 January 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, Martin LJ, Martinez M, North KE, Saccone NL, Schmidt S, et al. BMC Proceedings 2007, 1 (Suppl 1):S1 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Studying genetic determinants of natural variation in human gene expression using Bayesian ANOVA Cartier KC, Miscimarra L, Dazard JE, Song Y, Iyengar SK, Rao JS BMC Proceedings 2007, 1 (Suppl 1):S115 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Modeling the complex gene × environment interplay in the simulated rheumatoid arthritis GAW15 data using latent variable structural equation modeling Nock NL, Larkin EK, Morris NJ, Li Y, Stein CM BMC Proceedings 2007, 1 (Suppl 1):S118 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Fine-scale linkage disequilibrium mapping: a comparison of coalescent-based and haplotype-clustering-based methods Won S, Sinha R, Luo Y BMC Proceedings 2007, 1 (Suppl 1):S133 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Marker selection for whole-genome association studies with two-stage designs using dense single-nucleotide polymorphisms Li J BMC Proceedings 2007, 1 (Suppl 1):S136 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Two-stage analysis strategy for identifying the IgM quantitative trait locus Wang T, Lu Q, Torres-Caban M, Elston RC BMC Proceedings 2007, 1 (Suppl 1):S139 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Two-step intermediate fine mapping with likelihood ratio test statistics: applications to Problems 2 and 3 data of GAW15 Sinha R, Luo Y BMC Proceedings 2007, 1 (Suppl 1):S146 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Genome-wide association studies using an adaptive two-stage analysis for a case-control design Song K, Lu Q, Lin X, Waterworth D, Elston RC BMC Proceedings 2007, 1 (Suppl 1):S147 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Density-based clustering in haplotype analysis for association mapping Igo RP, Londono D, Miller K, Parrado AR, Quade SRE, Sinha M, Kim S, Won S, Li J, Goddard KAB BMC Proceedings 2007, 1 (Suppl 1):S27 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
An integrated genome-wide association analysis on rheumatoid arthritis data Zhang J, Zhu X, Cooper RS BMC Proceedings 2007, 1 (Suppl 1):S35 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
A logistic mixture model for a family-based association study Xing G, Xing C, Lu Q, Elston RC BMC Proceedings 2007, 1 (Suppl 1):S44 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Comparison of haplotyping methods using families and unrelated individuals on simulated rheumatoid arthritis data Li X, Li J BMC Proceedings 2007, 1 (Suppl 1):S55 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Comparison of affected sibling-pair linkage methods to identify gene × gene interaction in GAW15 simulated data Larkin EK, Morris NJ, Li Y, Nock NL, Stein CM BMC Proceedings 2007, 1 (Suppl 1):S66 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
A genome-wide linkage study of GAW15 gene expression data Kan D, Cooper R, Zhu X BMC Proceedings 2007, 1 (Suppl 1):S87 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Proceedings
Linkage studies of catechol-O -methyltransferase (COMT ) and dopamine-beta-hydroxylase (DBH ) cDNA expression levels Xing C, Torres-Caban M, Wang T, Lu Q, Xing G, Elston RC BMC Proceedings 2007, 1 (Suppl 1):S95 (18 December 2007) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Open access to novel dual flow chamber technology for in vitro cell mechanotransduction, toxicity and pharamacokinetic studies Anderson EJ, Knothe Tate ML BioMedical Engineering OnLine 2007, 6 :46 (4 December 2007) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Case report
Tissue is the issue-sarcoidosis following ABVD chemotherapy for Hodgkin's lymphoma: a case report Subbiah V, Ly UK, Khiyami A, O'Brien T Journal of Medical Case Reports 2007, 1 :148 (25 November 2007) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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