Mass spectrometry plays a crucial role in the realms of analytical chemistry, enabling the precise identification and quantification of biomolecules. Recent advancements in the field have enhanced sensitivity, speed, and accuracy in the analysis of complex samples. For instance, the development of hybrid mass spectrometers, such as quadrupole-Orbitrap and quadrupole-time-of-flight (Q-TOF) instruments, which combine the strengths of different mass analyzers, enable simultaneous analysis of multiple analytes in complex samples with improved resolution and sensitivity. Furthermore, advancements in ionization techniques, such as electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI), have expanded the range of analytes that can be analyzed by mass spectrometry. These developments have led to significant progress in various fields, including proteomics, metabolomics, environmental analysis, and pharmaceutical research. In addition to instrumentation, there have been significant advances in data analysis algorithms and sample preparation techniques, paving the way for more accessible and user-friendly mass spectrometry platforms.
As mass spectrometry continues to evolve, BMC Methods is launching this Collection on Advancements in mass spectrometry methods. We encourage submissions on:
- High-resolution mass spectrometry
- Sample preparation
- Quantitative analysis techniques
- Imaging mass spectrometry
- Single-cell mass spectrometry
- Spatial mass spectrometry
- Integration with multi-omics data
- Advances in software and data processing and analysis tools/algorithms
- Miniaturization and portable mass spectrometry
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