Rikard Holmdahl
Association of MHC and rheumatoid arthritis
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Citation: Arthritis Research & Therapy 2000 2:203
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Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid arthritis - studies in mice and men
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompati...
Citation: Arthritis Research & Therapy 2000 2:208 -
Association of MHC and rheumatoid arthritis: HLA polymorphisms in phenotypic variants of rheumatoid arthritis
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA, supporting a...
Citation: Arthritis Research & Therapy 2000 2:212 -
Association of MHC and rheumatoid arthritis: Association of RA with HLA-DR4 - the role of repertoire selection
Most patients with rheumatoid arthritis (RA) express HLA-DR4, HLA-DR1 or HLA-DR10. These alleles share a common amino acid motif in their third hypervariable regions: the shared epitope. In normals and patient...
Citation: Arthritis Research & Therapy 2000 2:217 -
Association of MHC and rheumatoid arthritis: Regulatory role of HLA class II molecules in animal models of RA - studies on transgenic/knockout mice
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked endogenous class II mo...
Citation: Arthritis Research & Therapy 2000 2:205