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Oral and Systemic Health

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New Content ItemAccording to the World Health Organisation, oral diseases pose a major public health burden worldwide, with almost 10% of the global population being affected by severe periodontal disease. Furthermore, numerous studies have demonstrated a connection between oral and overall health. For example, periodontal disease has been linked to many common non-communicable diseases, including cardiovascular disease, diabetes, respiratory disease, rheumatoid arthritis, kidney disease and cancer. Therefore, a greater understanding of oral-systemic health is required to improve our general health and support the United Nations Sustainable Development Goal 3, which aims to ensure healthy lives and promote well-being. BMC Oral Health has published this collection to bring together articles on oral-systemic health to highlight this need for knowledge.

The Collection considers:

  • Observational studies investigating associations between oral and systemic health.
  • Studies investigating common modifiable risk factors associated with oral and systemic diseases.
  • Research on the biological mechanisms connecting oral and systemic health.
  • Preventative strategies to improve oral and systemic health.

Meet the Guest Editors

Prof. Rodrigo Mariño

New Content Item (1)Rodrigo Mariño is a Professor of Population Oral Health at the Melbourne Dental School, The University of Melbourne, where he has worked since 2004. Rodrigo Mariño has a dental degree from the University of Chile, a master’s in public health, and a PhD from the University of Melbourne (Australia). Rodrigo’s research strongly focuses on oral health promotion and reducing inequalities in oral health status. Rodrigo has excellent research expertise in social epidemiology, dental workforce issues, public health, migrant health, Information and Communication Technology, gerontology, and population oral health. Rodrigo has published more than 160 papers in scientific journals, several major research reports and 34 book chapters. Rodrigo is currently member of the Editorial Board of three international, peer-reviewed journals and is a senior Editorial Board Member for BMC Oral Health.

Prof. Meghashyam Bhat

New Content ItemMeghashyam Bhat is a dental academic with a Ph.D in Dentistry (Oral Epidemiology) from the University of Adelaide, Australia and an MDS in Community Dentistry from the Rajiv Gandhi University of Health Sciences, Bengaluru, India. Additionally, he holds a Diploma and Membership from the Royal College of Surgeons England and the Royal College of Surgeons Edinburgh, UK, respectively. He has been working in dental academia for over two decades and has been heavily involved in teaching and research. Meghashyam Bhat is a Professor at the Rajiv Gandhi University of Health Sciences, Bengaluru, India and a Visiting Associate Professor at the Adelaide Dental School, The University of Adelaide, Australia. His research interests are in oral epidemiology, oral health inequalities, preventive dentistry, and health promotion. Prof. Bhat has published his research in several international open-access, peer-reviewed journals. He is also on the international advisory panel and editorial boards of other prestigious journals.


Collection Articles

  1. As periodontitis and dyslipidemia are diseases that occur with high incidence, the relationship between them has attracted much attention. Previous studies on these diseases have tended to focus on lipid param...

    Authors: Wanting Ma, Zhaolei Zou, Lisa Yang, Dongjia Lin, Junyi Guo, Zhongyan Shan, Qiannan Hu, Zhi Wang, Bin Li and Juan Fang
    Citation: BMC Oral Health 2024 24:508
  2. Decreased salivary secretion is not only a risk factor for carious lesions in Sjögren’s disease (SD) but also an indicator of deterioration of teeth with every restorative replacement. This study determined th...

    Authors: Grace Gomez Felix Gomez, Mei Wang, Zasim A. Siddiqui, Theresa Gonzalez, Oriana R. Capin, Lisa Willis, LaKeisha Boyd, George J. Eckert, Domenick T. Zero and Thankam Paul Thyvalikakath
    Citation: BMC Oral Health 2024 24:203
  3. Considering the inter-relationship between Diabetes Mellitus (DM) and oral tissues, assessment of oral health status in relation to glycemic control might be informative about the disease condition, which migh...

    Authors: Abe Elizabeth Oluwatoyin, Esan Arinola, Oyetola Elijah Olufemi and Adeleye Jokotade
    Citation: BMC Oral Health 2024 24:181
  4. The pathogenic microorganisms and clinical manifestations of caries and periodontitis are different, caries and periodontitis are usually discussed separately, and the relationship between them is ignored. Cli...

    Authors: Ying Wang, Fei Yang, Yuan Wang, Shuli Deng and Rui Zhu
    Citation: BMC Oral Health 2024 24:132
  5. The mouth is a central organ for communication and fluid intake, also for dying nursing home patients. This study describes the prevalence and severity of oral symptoms from nursing home admission until the da...

    Authors: Reidun K. N.M. Sandvik, Bettina S. Husebo, Geir Selbaek, Gunhild Strand, Monica Patrascu, Manal Mustafa and Sverre Bergh
    Citation: BMC Oral Health 2024 24:129
  6. Although the importance of oral and systemic healthcare for elderly people is increasing owing to the rapid ageing of the population in South Korea, studies on the relationship between oral health, systemic he...

    Authors: Jae-Eun Sin, Hye-Sung Kim, Inseong Hwang and Miwha Noh
    Citation: BMC Oral Health 2023 23:997
  7. Mounting evidence indicates potential associations between poor oral health status (OHS) and increased pneumonia risk. Relative pneumonia risk was assessed in the context of longitudinally documented OHS.

    Authors: Richard L. Berg, Ingrid Glurich, Aloksagar Panny, Frank A. Scannapieco, Jeffrey Miecznikowski, Jeffrey VanWormer and Amit Acharya
    Citation: BMC Oral Health 2023 23:950
  8. The muscle quality index (MQI) is a measurement of muscle quality that is directly related to overall health. There has been little study on the relationship between the muscle quality index and periodontitis ...

    Authors: Jukun Song, Yadong Wu, Hong Ma and Junmei Zhang
    Citation: BMC Oral Health 2023 23:918
  9. The purpose of this study was to investigate the relationships of oral health status and swallowing function with cognitive impairment in community-dwelling older adults from Changsha, Hunan Province, China.

    Authors: Yong Chen, Canyang Li, Yongmei Fan, Lili Jiao, Matthew Silverman, Masashi Ishimaru, Jing Wang, Alice J. Van Pelt and Rumi Wang
    Citation: BMC Oral Health 2023 23:912
  10. Although the relationship between oral and physical frailty in older adults has been investigated, few studies have focused on the working-age population. This study examined the relationships of the number of...

    Authors: Rie Nagao-Nishiwaki, Akinobu Nishimura, Makoto Ohtsuki, Toshihiro Kato and Akihiro Sudo
    Citation: BMC Oral Health 2023 23:711
  11. The effects of oral health on mortality have been reported; however, the association between mortality and Oral Health-Related Quality of Life (OHQOL) is unknown. We investigated the effect of OHQOL on total m...

    Authors: Nishiki Arimoto, Rumi Nishimura, Teruo Kobayashi, Mayuka Asaeda, Toru Naito, Masaaki Kojima, Osami Umemura, Makoto Yokota, Nobuhiro Hanada, Takashi Kawamura, Kenji Wakai and Mariko Naito
    Citation: BMC Oral Health 2023 23:708
  12. We aimed to investigate the association between oral health and cognitive function in a sample of older adults from a Chinese rural community.

    Authors: Wenjia Gu, Jialin Li, Fei Li, Teck-Ek Ho, Xiping Feng, Yingzhe Wang, Min Fan, Mei Cui, Kelin Xu, Xingdong Chen, Haixia Lu and Yanfeng Jiang
    Citation: BMC Oral Health 2023 23:640
  13. Little is currently known about HIV-related parameters that may increase the risk for oral ulcers during the COVID-19 pandemic. This study aimed to overcome this gap in research by assessing the associations b...

    Authors: Morenike Oluwatoyin Folayan, Roberto Ariel Abeldaño Zuñiga, Jorma I. Virtanen, Nourhan M. Aly, Oliver C Ezechi, Joanne Lusher, Maha El Tantawi and Annie L Nguyen
    Citation: BMC Oral Health 2023 23:600
  14. The association between dyslipidemia, diabetes and alterations in periodontal health are inconsistent. The aim of this study was to determine the association between dyslipidemia, diabetes and periodontal dise...

    Authors: Fatemeh Ayoobi, Somaye Salari Sedigh, Parvin Khalili, Zeinab Sharifi, Hamid Hakimi, Farimah Sardari and Zahra Jamali
    Citation: BMC Oral Health 2023 23:549
  15. To assess if the results following intake of a diet using an Okinawan-based Nordic diet (OBND) over one month differs in endocrinological, periodontal clinical outcome, and serum cytokine levels compared to a ...

    Authors: G. Rutger Persson, Cecilia Widén, Björn Wohlfart, Klas Sjöberg, Stig Steen, Michael D. Coleman and Helene Holmer
    Citation: BMC Oral Health 2023 23:544
  16. Beta-Thalassemia is the most common human inherited disease, directly impacting patients’ physical and psychosocial aspects. The present study evaluated oral health status, oral health-related quality of life ...

    Authors: Fatemeh Abbasi, Adel Tabesh, Amirmohammad Yavari, Rasoul Makaremi, Omid Bizhani and Mahboobeh Mahmood
    Citation: BMC Oral Health 2023 23:493
  17. Previous observational studies have shown that people with dental scaling (DS) had decreased risk of stroke. However, limited information is available on the association between DS and poststroke outcomes. The...

    Authors: Li-Chin Sung, Chuen-Chau Chang, Chun-Chieh Yeh, Chia-Yen Lee, Chaur-Jong Hu, Yih-Giun Cherng, Ta-Liang Chen and Chien-Chang Liao
    Citation: BMC Oral Health 2023 23:487
  18. Periodontal disease can activate an immune process linked to systemic diseases, including atrial fibrillation. However, the relationship between periodontal disease and atrial fibrillation remains unclear.

    Authors: Jung-Hyun Park, Hyungwoo Lee, Jin-Woo Kim and Tae-Jin Song
    Citation: BMC Oral Health 2023 23:461
  19. Poor dental health is correlated with an increased risk of cancer. Using a nationwide population cohort database, we investigated which cancer is highly associated with poor dental health and which dental indi...

    Authors: Eun Joo Kang, Seok-joo Moon, Kyoungmin Lee, In Hae Park, Jung Sun Kim and Yoon Ji Choi
    Citation: BMC Oral Health 2023 23:418
  20. Considering the rising prevalence of metabolic syndrome (MetS), this study aimed to investigate the relationship between MetS and its components with oral and dental health in the adult population of the Azar ...

    Authors: MohammadAmin Tarighat Esfanjani, Neda Gilani, Ali Tarighat Esfanjani, Amir Mohammad Nourizadeh, Elnaz Faramarzi and Somayeh Hekmatfar
    Citation: BMC Oral Health 2023 23:370
  21. Diabetic patients are not often aware of relationship between diabetes mellitus (DM) and periodontal diseases, and the researchers recommend further knowledge enhancement of diabetic patients in this regard. T...

    Authors: Atousa Haghdoost, Soheila Bakhshandeh, Sajjad Tohidi, Zahra Ghorbani and Mahshid Namdari
    Citation: BMC Oral Health 2023 23:359
  22. Patients with chronic kidney disease undergoing hemodialysis are often colonized by Candida species with high possibility of fungal infections. The purposes of this study were to determine the prevalence of Candi...

    Authors: Faezeh Mohammadi, Maliheh Charkhchian and Monirsadat mirzadeh
    Citation: BMC Oral Health 2023 23:261
  23. This cross-sectional study aimed to investigate the association between periodontitis and osteoporosis among US adults as well as the subgroup of menopausal women.

    Authors: Jing Peng, Jianming Chen, Yucheng Liu, Jun Lyu and Bin Zhang
    Citation: BMC Oral Health 2023 23:254
  24. Uric acid, a formerly-known antioxidant that has recently been linked to numerous inflammatory diseases as a pro-inflammatory and -oxidative mediator in pathological conditions. It is imperative to reassess th...

    Authors: Lu-wen Ye, Li Zhao, Ze-song Mei, Ying-hong Zhou and Ting Yu
    Citation: BMC Oral Health 2023 23:178
  25. Previous studies have indicated an association between oral hypofunction and frailty in community-dwelling older adults. However, this issue has not been evaluated in institutionalized older patients. We aimed...

    Authors: Karla Cruz-Moreira, Ludwig Alvarez-Cordova, Carla González-Palacios Torres, Peter Chedraui, José Jouvin, José Juan Jiménez-Moleón and Rocío Barrios-Rodríguez
    Citation: BMC Oral Health 2023 23:140
  26. This cross-sectional survey aimed to evaluate the oral health behaviour of patients prior to endoprosthesis (EP), as well as the handling of oral health topics by German orthopaedic surgeons.

    Authors: Gerhard Schmalz, Carina Lenzen, Florentine Reuschel, Fabian Fenske, Rainer Haak, Szymon Goralski, Andreas Roth and Dirk Ziebolz
    Citation: BMC Oral Health 2023 23:92
  27. Dental care in cancer patients tends to be less prioritized. However, limited research has focused on major dental treatment events in cancer patients after the diagnosis. This study aimed to examine dental tr...

    Authors: Areum Han, Eun-Gee Park, Jeong-Hwa Yoon, Ji-Yeob Choi, Hee-Kyung Park and Seokyung Hahn
    Citation: BMC Oral Health 2023 23:64
  28. Hyperlipidaemia may play a significant role in the interrelationship between type 1 diabetes (T1D) and periodontal disease. A potential mechanism that links these three aspects together is the oral microbiota....

    Authors: Caitlin A. Selway, Emilija D. Jensen, Alexia S. Pena, Gabrielle Smart and Laura S. Weyrich
    Citation: BMC Oral Health 2023 23:15
  29. Oral mucositis (OM) is a major side effect of cancer therapy, which is associated with significant symptoms, treatment delays and increased costs for the health system. It is an important component of the qual...

    Authors: O. Di Fede, F. Canepa, L. Maniscalco, P. Tozzo, D. Matranga and G. Giuliana
    Citation: BMC Oral Health 2023 23:4
  30. Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate...

    Authors: Burak G. Yildirim, Cemilenur Aksit, Mesut Mutlu, Mari Ainola, Kari K. Eklund, Jaakko Leskelä, Pirkko Pussinen and Arzu Beklen
    Citation: BMC Oral Health 2022 22:627
  31. Sleep is crucial for survival. Sleep deprivation causes ROS accumulation and, consequently, oxidative stress. The goal of the study was to evaluate gingival crevicular fluid (GCF) levels of the oxidative stres...

    Authors: Qianwen Yin, Chao Liu, Han Bao, Size Li, Zhuwei Huang, Deao Gu, Liping Xiong and Leiying Miao
    Citation: BMC Oral Health 2022 22:616
  32. Fibroblast growth factor 21 (FGF21) is closely associated with metabolic syndrome (MetS). An alteration of FGF21 is possibly affected by periodontitis. The present study aimed to investigate the levels of seru...

    Authors: Teerat Sawangpanyangkura, Panwadee Bandhaya, Pattanin Montreekachon, Anongwee Leewananthawet, Arintaya Phrommintikul, Nipon Chattipakorn and Siriporn C. Chattipakorn
    Citation: BMC Oral Health 2022 22:570
  33. 2019 Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The COVID-19 pandemic has already had a serious influence on human exist...

    Authors: Churen Zhang, Yuzhe Sun, Min Xu, Chang Shu, Zhaoguo Yue, Jianxia Hou and Dongchen Ou
    Citation: BMC Oral Health 2022 22:520
  34. Oral streptococci represent the causing microorganism for infective endocarditis (IE) in many patients. The impact of oral infections is questioned, and it has been suggested that bacteraemia due to daily rout...

    Authors: Therese Thoresen, Stina Jordal, Stein- Atle Lie, Friederike Wünsche, Martha Rolland Jacobsen and Bodil Lund
    Citation: BMC Oral Health 2022 22:491
  35. Periodontal disease is the most common oral health problem among individuals living with disabilities. Any physical impairment and/or mental handicap can compromise the capability to perform oral health care. ...

    Authors: Amare Teshome Tefera, Biruk Girma, Aynishet Adane, Abebe Muche, Tadesse Awoke Ayele, Kefyalew Ayalew Getahun, Zelallem Aniley, Semira Ali and Simegnew Handebo
    Citation: BMC Oral Health 2022 22:343
  36. Marfan syndrome (MFS) is a systemic disorder of connective tissues caused by insufficient elastic fiber formation that leads to structural weakness and results in various tissue disorders, including cardiovasc...

    Authors: Kouta Umezawa, Takako Kajiwara, Kyoko Ishii, Tatsuya Hasegawa, Shigeto Suzuki, Masato Nakano, Mayu Sawaguchi, Venkata Suresh Venkataiah, Yoshio Yahata, Koki Ito, Yoshikatsu Saiki and Masahiro Saito
    Citation: BMC Oral Health 2022 22:336
  37. Post-stroke inpatients are at risk of poor oral health for a number of reasons. The aim of this study was to assess the oral health status of post-stroke patients and also to explore the factors that may influ...

    Authors: Júlia Moldvai, Mercédesz Orsós, Eszter Herczeg, Eszter Uhrin, Márton Kivovics and Orsolya Németh
    Citation: BMC Oral Health 2022 22:234